For enhanced safety, the front and rear seat shoulder belts of the Mercedes GLC Coupe have pretensioners to tighten the seatbelts and eliminate dangerous slack in the event of a collision and force limiters to limit the pressure the belts will exert on the passengers. The Nissan Murano doesn’t offer pretensioners for its rear seat belts.
The GLC Coupe’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Murano doesn’t offer pre-crash pretensioners.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the GLC Coupe. But it costs extra on the Murano.
When descending a steep, off-road slope, the GLC Coupe’s standard Downhill Speed Regulation allows you to creep down safely. The Murano doesn’t offer Downhill Speed Regulation.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The GLC Coupe has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The Murano doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.
Both the GLC Coupe and Murano have rear cross-traffic warning, but the GLC Coupe has Active Brake Assist (automatically applies the brakes) to better prevent a collision when backing near traffic. The Murano’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the GLC Coupe and the Murano have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available lane departure warning systems.

